Vice President, Clinical Development

GENERAL SCOPE AND SUMMARY

Sensorium Therapeutics is searching for a creative, resourceful, integrative thinker for a highly visible role responsible for leading the clinical development strategy and clinical-related activities for SNTX-2643 and Sensorium’s pipeline efforts. The position is responsible for providing subject matter expertise in the development and execution of Clinical Development activities, including Phase 1–3 study and clinical research organization oversight, provision of strategic guidance and oversight of potential clinical sites and non-CRO clinical development vendors (for example, qEEG and pharmacokinetic modeling), and collaboration with key national opinion leaders to guide pipeline and clinical development strategy.

The ideal candidate will embrace a collaborative and innovative culture towards continuous improvement, guided by the principle of patients first. They must thrive working in a fast-paced environment while remaining agile, proactive, and curious.

ROLES AND RESPONSIBILITIES

• Provides leadership to SNTX-2643 clinical team members in support of clinical development strategic needs
• Collaborates with the Chief Medical Officer to support pipeline Clinical Development strategy and activities, but is not directly responsible for pipeline strategy or activities
• Maintains and provides subject matter expertise as Clinical Development lead forSNTX-2643
• Collaborates with Finance, Research and Development, and business development to translate clinical insights and data gaps into corporate strategy
• Cultivates partnerships with cross-functional partners such as platform, pre-clinical,CMC, pharmacovigilance, regulatory, operations, program management, and finance to provide clinical leadership in support of relevant therapeutic and disease area initiatives
• Works closely with Regulatory and Clinical Operations to ensure optimal collaboration and the inclusion of external clinicians and KOLs in clinical trial planning, enrollment, and interpretation
• Interacts with investigators, KOLs, research institutions, and internal Sensorium departments to oversee and facilitate Clinical Development objectives, ensuring the medical and scientific merit of company activities
• Supports short- and long-term goals of Clinical Development with respect to the prioritization of research interests and of desired collaborations with specific investigators and institutions
• Ensures alignment of SNTX-2643 clinical development activities with corporate strategy, program plans, and objectives
• Provides oversight and leadership in the review and approval of external resources,communications, and publications to ensure medical accuracy, objectivity, and fair balance
• Facilitates cross-functional teams in performing post-hoc data analyses and identifying opportunities to address clinical data gaps
• Manages and regularly meets with a network of national thought leaders to support the successful execution of Clinical Development tactics
• Represents Sensorium at scientific and clinical congress meetings
• Interacts with other departments including business development, finance, pharmacovigilance, legal, and regulatory

QUALIFICATIONS

REQUIRED:

• MD or DO, or PhD/PharmD required
• Minimum of 10 years of biopharmaceutical industry clinical development experience, with a strong track record of successful clinical program execution in the field of CNS/Psychiatry
• Experience with Phases 1-3 clinical development; knowledge and experience of building clinical development infrastructure aligned with the needs of an early-stage growing organization
• Working knowledge of ICH/GCP/FDA requirements and applicable global regulatory expectations, interpretation of clinical data and generation of supporting regulatory submissions of clinical study documents
• Understanding of the general healthcare environment in and outside of the US, including laws, regulations, and evolving market access trends and issues

PREFERRED:

• Demonstrated CNS clinical development experience, with psychiatry or neuropsychiatry strongly preferred (anxiety, mood, or related indications)
• Experience with acute or rapid-onset treatment paradigms and the design and endpoint challenges they create, including challenge or provocation models
• Familiarity with CNS biomarkers, including quantitative EEG, and with pharmacokinetic and pharmacodynamic modeling as a decision-making tool
• Experience with successful NDA submissions and approvals and interactions with regulatory agencies highly desired

CORE COMPETENCIES:

• Sets and maintains high standards for self and team in area of responsibility
• Must possess excellent communication skills with experience interacting with executive leadership and external stakeholders and the ability to flexibly tailor effective communication to multiple social styles
• Recognized for strong leadership, cross-functional collaboration, and relationship-building with both internal and external stakeholders
• Highly motivated, decisive, and results-oriented individual with the flexibility and creativity to excel in a rapidly growing and changing environment

COMPENSATION AND BENEFITS

Base salary range: Actual base salary will be determined by role-relevant experience, demonstrated capability, and internal equity, and may fall anywhere within the range.

In addition to a competitive base salary, this position includes:

• Performance bonus and equity
• Medical, dental, and vision coverage for employees and dependents
• 401(k)
• Company-paidlife and disability insurance
• Unlimited paid time off, company holidays, and paid parental leave
• Support for scientific conferences, continuing medical education, and professional development

WORK LOCATION

This position is remote and open to candidates anywhere in the United States. Sensorium is headquartered in Boston, and the role carries a regular onsite cadence: travel to Boston for company meetings, plus investigator meetings, health authority interactions, site visits, and scientific congresses. Candidates who prefer a Boston-area hybrid arrangement are equally welcome.

HOW TO APPLY

Qualified candidates are encouraged to submit their resumes to careers@sensorium.bio. Applications will be reviewed on a rolling basis and accepted until the position is filled. Candidates unsure whether their background fits are encouraged to reach out. We are also open to discussing interim or consulting arrangements for candidates available immediately.

EQUAL EMPLOYMENT OPPORTUNITY

Sensorium Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, pregnancy, sexual orientation, gender identity or expression, national origin, ancestry, age, genetic information, physical or mental disability, protected veteran status, military service, marital status, or any other characteristic protected by federal, state, or local law.

Sensorium provides reasonable accommodations for applicants with disabilities and for those who need accommodation for religious reasons. If you need an accommodation at any stage of the application or interview process, please contact careers@sensorium.bio.

This job description is not intended to be an exhaustive list of all duties, responsibilities, or aspects of the position. Duties may be added, and this description may be amended, at any time at the sole discretion of Sensorium Therapeutics.